Coenzyme Q10: what is known about the health risks – and what isn’t?

BfR FAQ of 10 November 2023

Coenzyme Q10 is essential for the metabolism, but can be produced by the body itself. It is an important component of the mitochondria, which are responsible for the energy metabolism in the body’s cells. Coenzyme Q10 is involved in the electron transport in the mitochondria and, as an antioxidant, can protect cells from oxidative damage caused by so-called “free radicals”. Tissues with a high energy requirement, such as the heart, kidneys, liver and muscles, have particularly high levels of coenzyme Q10. Coenzyme Q10 is not an essential nutrient (to be supplied by food), as this substance is produced in sufficient quantities by a healthy body itself. In healthy individuals following a varied, balanced diet, a sufficient supply of coenzyme Q10 is guaranteed.

Regarding the health assessment of the two forms of the coenzyme – ubiquinol and ubiquinone – there are currently gaps in knowledge and scientific uncertainties due to insufficient data.

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