Toxoplasma gondii sources quantified (EJP TOXOSOURCE)

01/2020-06/2022

Funding programme / funding institution: Europäische Union

Grant number: 773830

Project homepage: https://onehealthejp.eu/jrp-toxosources/

Project description:

The TOXOSOURCE project will address the research question - What are the relative contributions of the different sources of T. gondii infection? - using several multidisciplinary approaches and novel and improved methods to yield the most robust estimates possible that can inform risk management and policy makers.

The main outcomes of TOXOSOURCE are quantitative estimates of the contribution of the main sources and transmission routes of T. gondii infection based on improved source attribution models, new data filling the key knowledge gap about the role of increasingly popular but unstudied ready-to-eat (RTE) fresh produce, a novel serological method that aims to specifically detect infections caused by oocysts, and a novel typing method to improve preparedness to detect introduction of atypical T. gondii strains by import and to trace the infection sources in outbreaks.

All the results are integrated to contribute to developing efficient interventions at national, regional, European and global levels. TOXOSOURCE will have immediate and long-term societal impact, and has potential, ability and ambition to advance science.

Project partners:

  • Statens Serum Institute
  • Istituto Superiore di Sanitá
  • Rijksinstituut Voor Volksgezondheid En Milieu
  • Institut für Eipdemiologie (IfE): Nationales Referenzlabor für Toxoplasmose
  • Robert Koch-Institut
  • Universidad Complutense de Madrid
  • Danmarks Tekniske Universitet
  • ANSES - Französisch Agentur für Lebensmittel, Umwelt und Arbeitssicherheit
  • University of Surrey
  • National Veterinary Institute
  • National Institut for Agricultural and Veterinary Research, Portugal
  • National Veterinary Instiute (Schweden)

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