Unit Diagnostics, Pathogen Characterisation, Parasites in Food
Our tasks
Focus of work
Scientific work of the Unit focuses on the following topics:
- Diagnosis and fine differentiation of bacterial and parasitic zoonotic pathogens using phenotyping, serological and molecular biology methods
- Development and validation of methods for pathogen isolation and characterisation
- Assessment of risks resulting from bacterial and parasitic zoonotic pathogens
- Assessment and provision of advice on the potential for misuse of hazardous biological pathogens
- Investigation of pathogen-host interactions using acknowledged animal models
- Mechanisms and effects of horizontal gene transfer on the emergence of novel food-related zoonotic pathogens
- Molecular mechanisms and the importance of transduction for horizontal gene transfer (in particular bacteriophages)
- Molecular-genetic characterisation of bacterial genomes and plasmids of pathogenic variants and related environmental isolates thereof; analysis of genomic islands
Laboratories
The unit comprises the National Reference Laboratory for Trichinella, the consultant laboratory for Leptospira and two consultant laboratories certified by the German Veterinary Society (DVG), the DVG consultant laboratory for Vibrio spp. and the DVG consultant laboratory for Yersinia spp., respectively. The work is based on EU Directive 2003/99/EC on the monitoring of zoonoses and zoonotic agents. In addition to its official federal duties as reference and consultant laboratories, the unit is involved in several national, European and international research activities and participates together with partner institutes, universities and laboratories in various funded research programs.
Further information
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Reference Laboratories
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Consultant Laboratories
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Specialist Publications
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Detailed information on the work of BfRshort forGerman Federal Institute for Risk Assessment in microbial risk